<p style="font-weight: 400;">Researchers at the Spanish National Cancer Research Centre (CNIO), led by Dr. Mariano Barbacid, have achieved a <a href="https://www.dailymail.co.uk/health/article-15512253/Huge-pancreatic-cancer-breakthrough-scientists-achieve-permanent-disappearance-disease-new-triple-threat-approach.html">significant breakthrough</a> in the treatment of pancreatic ductal adenocarcinoma (PDAC), the most common and deadly form of pancreatic cancer. In a study <a href="https://www.pnas.org/doi/10.1073/pnas.2523039122">published</a> in the journal <em data-path-to-node="0" data-index-in-node="288">PNAS</em>, the team demonstrated that a new triple-drug combination therapy can completely and permanently eliminate pancreatic tumors in experimental mouse models.</p>
<p style="font-weight: 400;" data-path-to-node="1">Pancreatic cancer has long been considered one of the most difficult &#8220;incurable&#8221; diseases, characterized by a five-year survival rate of less than 11%. Its resilience is largely due to the KRAS oncogene, a mutation present in approximately 90% of cases. Although KRAS was historically considered &#8220;undruggable,&#8221; recent advances have enabled the development of RAS inhibitors. However, these single-target drugs often fail in the long term because tumors quickly develop resistance by utilizing alternative survival pathways.</p>
<p style="font-weight: 400;" data-path-to-node="2">The CNIO team’s innovation lies in a &#8220;triple-threat&#8221; approach that blocks three independent signaling nodes simultaneously: downstream (RAF1), upstream (EGFR), and orthogonal (STAT3) pathways. By targeting these three routes, the therapy effectively &#8220;traps&#8221; the cancer cells, preventing them from outmaneuvering the treatment. The researchers tested this across various models, including mice with human pancreatic tissue and mice genetically engineered to model the disease. In all cases, the combination — consisting of the drugs daraxonrasib (KRAS inhibitor), afatinib (EGFR inhibitor), and SD36 (STAT3 degrader) — resulted in complete tumor regression without the appearance of resistance for over 200 days post-treatment. Crucially, the therapy was well-tolerated with no significant toxicities.</p>
<p style="font-weight: 400;" data-path-to-node="3">The implications of this study are profound. Currently, patients rely on decades-old cytotoxic drugs like gemcitabine or highly toxic combinations like FOLFIRINOX, which offer limited benefits. This new research provides a roadmap for human clinical trials, suggesting that the key to curing pancreatic cancer lies in combination therapies rather than monotherapy.</p>
<p style="font-weight: 400;" data-path-to-node="4">While the results are promising, experts note limitations: the success was observed in healthy laboratory mice, and human physiology may present different challenges. Nevertheless, the Spanish government and the international scientific community have hailed the discovery as a potential turning point. If these results can be replicated in humans, it could transform the prognosis for a disease that currently kills more than half of its victims within three months of diagnosis.</p>


Pancreas cancer, illustration

‘Triple-Threat’ Breakthrough: New Therapy Eradicates Pancreatic Tumors In Preclinical Study

Cancer

Pancreatic cancer

<p>Tatiana Schlossberg, granddaughter of the 35th U.S. president, John F. Kennedy, died on Tuesday after revealing in a November essay that she had been diagnosed with a rare form of leukemia. She was 35.</p>
<p>Her passing was announced by her family in a social media post from the John F. Kennedy Presidential Library and Museum.</p>
<p>&#8220;Our beautiful Tatiana passed away this morning. She will always be in our hearts,&#8221; the family wrote.</p>
<p>Schlossberg was a climate change and environmental journalist and the second child of JFK&#8217;s daughter, former U.S. diplomat Caroline Kennedy, and the designer-artist Edwin Schlossberg.</p>
<p>In a New Yorker essay published in November, Schlossberg said she had been diagnosed with acute myeloid leukemia with a rare mutation, a cancer of the blood and bone marrow.</p>
<p>At the time, she also criticized her cousin Robert F. Kennedy Jr., the U.S. health secretary, for being a vaccine skeptic and cutting funding for cancer research.</p>
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<p>According to the <a href="https://my.clevelandclinic.org/health/diseases/6212-acute-myeloid-leukemia-aml">Cleveland Clinic</a>, acute myeloid leukemia &#8220;typically happens when certain genes or chromosomes mutate (change). AML usually affects people age 60 and older, but it can also affect younger adults and children. [It] is an aggressive cancer that can be life-threatening.&#8221;</p>
<p>The illness only affects about 4 in 100,000 adults per year.</p>
<p>Blood Cancer United <a href="https://bloodcancerunited.org/resources/newsroom/fda-approves-new-drug-treat-advanced-aml-adults">reported</a> in November that the FDA approved a new drug called ziftomenib to treat those with advanced AML with an NPM1 gene mutation.</p>
<p>&#8220;In a clinical trial, 21.4% of patients treated with ziftomenib went into a full remission or remission with partial recovery of blood counts, which means there were no signs of cancer cells in the bone marrow, but not all blood counts had returned to normal.&#8221;</p>
<p>(Reporting by Bhargav Acharya in Toronto; Editing by Doina Chiacu)</p>


Tatiana Schlossberg

Tatiana Schlossberg, Granddaughter Of JFK, Dies Of Rare Form Of Leukemia

General

John F. Kennedy (JFK)

Robert F. Kennedy Jr.

U.S.

<p><span style="font-weight: 400;">Legendary recording artist Barry Manilow revealed that he’s been diagnosed with lung cancer and will need to reschedule some of his upcoming concerts.</span></p>
<p><span style="font-weight: 400;">The 82-year-old “Copacabana” singer gave an update to fans with a statement posted to Instagram.</span></p>
<p><span style="font-weight: 400;">&#8220;The MRI discovered a cancerous spot on my left lung that needs to be removed,&#8221; Manilow wrote in the statement.</span></p>
<p><span style="font-weight: 400;">&#8220;It&#8217;s pure luck (and a great doctor) that it was found so early,&#8221; he went on. &#8220;The doctors do not believe it has spread, and I&#8217;m taking tests to confirm their diagnosis.&#8221;</span></p>
<p><span style="font-weight: 400;">The singer said he is &#8220;going into surgery to have the spot removed,&#8221; which means he’ll have to reschedule the January shows on his “Christmas: A Gift of Love” series. He promised to return to the stage on Valentine’s Day weekend in 2026.</span></p>
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<p><span style="font-weight: 400;">Manilow apologized for the inconvenience, telling fans, &#8220;We were all looking forward to the January shows and hate having to move everything around.” He also urged his followers to stay vigilant when it comes to their health.</span></p>
<p><span style="font-weight: 400;">“I hope you have a wonderful Christmas and a Happy New Year. And remember, if you have even the slightest symptom, get tested!&#8221; the statement concluded.</span></p>
<p><span style="font-weight: 400;">Manilow, a Grammy-winning singer-songwriter and producer, rose to fame in the 1970s with a string of pop hits like “Mandy,” “Copacabana,” and “Can’t Smile Without You.” Before becoming a superstar, he built a career writing jingles and arranging music for major artists such as Bette Midler. Manilow’s career spans five decades, during which he has sold millions of records and acquired a devoted fan base who call themselves “Fanilows.”</span></p>


Barry Manilow

Barry Manilow Reveals Lung Cancer Diagnosis

Entertainment

Music

<p>Former Nebraska Republican Senator Ben Sasse revealed on Tuesday that he has been diagnosed with metastasized, stage-four pancreatic cancer, adding that he is &#8220;gonna die.&#8221;</p>
<p>Sasse, a 53-year-old husband and father of three, <a href="https://x.com/BenSasse/status/2003483746540965891">announced</a> the tragic news in a lengthy social media post, saying that the diagnosis is a &#8220;death sentence.&#8221;</p>
<p>&#8220;Friends- This is a tough note to write, but since a bunch of you have started to suspect something, I’ll cut to the chase: Last week I was diagnosed with metastasized, stage-four pancreatic cancer, and am gonna die,&#8221; Sasse wrote. &#8220;Advanced pancreatic is nasty stuff; it’s a death sentence. But I already had a death sentence before last week too — we all do.&#8221;</p>
<p>Sasse, who represented Nebraska in the U.S. Senate for eight years, resigned from his seat in 2022 and, shortly after, was appointed the president of the University of Florida. He <a href="https://www.dailywire.com/news/former-gop-senator-ben-sasse-announces-he-is-stepping-down-as-university-of-florida-president">stepped down</a> from leading the University of Florida in July of 2024 after revealing that his wife was dealing with a serious medical condition and had suffered an aneurysm and a series of strokes. During his time as president of Florida, Sasse took a strong stance against anti-Israel protesters in the wake of Hamas&#8217; terrorist attack on Israel and said the university would &#8220;draw a hard line at unlawful action.&#8221;</p>
<p>Sasse was a staunch pro-life advocate in the U.S. Senate and constantly pushed the U.S. government to remain tough on China. He has also been a strong critic of President Donald Trump since Trump first stepped into the political spotlight in 2016.</p>
<p>The former Republican senator said on Tuesday, &#8220;I’ve got less time than I’d prefer. This is hard for someone wired to work and build, but harder still as a husband and a dad.&#8221; Sasse added that he is relying on his Christian faith to get him through his recent cancer diagnosis.</p>
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<p>&#8220;There’s not a good time to tell your peeps you’re now marching to the beat of a faster drummer — but the season of advent isn’t the worst. As a Christian, the weeks running up to Christmas are a time to orient our hearts toward the hope of what’s to come,&#8221; he said. &#8220;Not an abstract hope in fanciful human goodness; not hope in vague hallmark-sappy spirituality; not a bootstrapped hope in our own strength (what foolishness is the evaporating-muscle I once prided myself in). Nope — often we lazily say &#8216;hope&#8217; when what we mean is &#8216;optimism.&#8217; To be clear, optimism is great, and it’s absolutely necessary, but it’s insufficient. It’s not the kinda thing that holds up when you tell your daughters you’re not going to walk them down the aisle. Nor telling your mom and pops they’re gonna bury their son.&#8221;</p>
<p>&#8220;I’ll have more to say. I’m not going down without a fight,&#8221; he continued. &#8220;One sub-part of God’s grace is found in the jawdropping advances science has made the past few years in immunotherapy and more. Death and dying aren’t the same — the process of dying is still something to be lived. We’re zealously embracing a lot of gallows humor in our house, and I’ve pledged to do my part to run through the irreverent tape.&#8221;</p>


Ben Sasse

Former Senator Ben Sasse Reveals Stage-Four Cancer Diagnosis: ‘I’ve Got Less Time Than I’d Prefer’

Health

U.S. Senate

<p><span style="font-weight: 400;">Actor James Van Der Beek announced that he’s selling off memorabilia from some of his best-known entertainment projects to help pay for his medical bills.</span></p>
<p><span style="font-weight: 400;">The 48-year-old father of six was diagnosed with Stage 3 colorectal cancer last year. Van Der Beek said in a </span><a href="https://people.com/james-van-der-beek-auctions-dawsons-creek-varsity-blues-memorabilia-exclusive-11847179"><span style="font-weight: 400;">statement</span></a><span style="font-weight: 400;"> to People that he’s teaming up with Propstore to offer pieces from his collection during the company’s Winter Entertainment Memorabilia Live Auction running December 5-7.</span></p>
<p><span style="font-weight: 400;">Items up for grabs include props from the popular teen drama “Dawson’s Creek,” such as the necklace Dawson (Van Der Beek) gave Joey (Katie Holmes) for prom, which the outlet noted is estimated to go for as much as $52,800. The outfit Van Der Beek wore in the pilot episode is expected to nab close to $4,000.</span></p>
<p><span style="font-weight: 400;">There will also be items from the popular teen sports drama “Varsity Blues” (1999), such as the cleats and West Canaan Coyotes hat that Van Der Beek wore while portraying Jonathan “Mox” Moxon.</span></p>
<p><span style="font-weight: 400;">“I’ve been storing these treasures for years, waiting for the right time to do something with them, and with all of the recent unexpected twists and turns life has presented recently, it’s clear that the time is now,” Van Der Beek told People.</span></p>
<p><span style="font-weight: 400;">He added, “While I have some nostalgia tugging at me as I part with these items, it feels good to be able to offer them through Propstore’s auction to share with those who have supported my work over the years.”</span></p>
<p><span style="font-weight: 400;">The outlet noted that 100% of the proceeds would go toward helping fund the actor’s cancer treatments.</span></p>
<p><span style="font-weight: 400;">In September, Van Der Beek was forced to drop out of a “Dawson’s Creek” reunion event at the last minute due to a stomach illness. </span></p>
<p><span style="font-weight: 400;">“I have been looking forward to this night for months and months ever since my angel Michelle Williams said she was putting it together,” the “Dawson’s Creek” alum said in the recorded message at the time, as The Daily Wire previously </span><a href="https://www.dailywire.com/news/james-van-der-beek-sends-video-message-to-dawsons-creek-reunion-after-illness-knocks-him-out"><span style="font-weight: 400;">reported</span></a><span style="font-weight: 400;">. “I can’t believe I’m not there. I can’t believe I don’t get to see my castmates, my beautiful cast, in person.”</span></p>
<p><span style="font-weight: 400;">“And just I want to stand on that stage and thank every single person in the theater for being here tonight,” Van Der Beek continued. “From the cast to the crew to everybody who’s doing anything and has been so generous, and especially every single last one of you – you are the best fans in the world.”</span></p>


James Van Der Beek

Actor James Van Der Beek To Auction Show Memorabilia To Fund Cancer Treatments

James Van Der Beek Auctioning 'Dawson's Creek,' 'Varsity Blues' Items To Pay For Cancer Treatments

Celebrities

Movies

Television

<p><span style="font-weight: 400;">As history shows, nearly every civilization has progressed and evolved using some form of alcohol. But no civilization in history has ever experimented with the types of industrialized THC products Western countries are now recklessly legalizing, commercializing, and normalizing. We might pause to ask ourselves why zero Asian countries have done so and why China is so anxious </span><a href="https://www.npr.org/2024/06/24/1238497863/chinese-marijuana-farms-new-mexico"><span style="font-weight: 400;">to promote</span></a><span style="font-weight: 400;"> this cultural suicide weapon here.</span></p>
<p><span style="font-weight: 400;">A 2023 </span><a href="https://urldefense.com/v3/__https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01917-8/fulltext__;!!JA_k2roV-A!F0P_XFB6ND8ziqH2ovImdot2Tze_kgHA6TLYEc8Ifkn-grY-c9CqSJv-NPamf6v0PFrGk-6w--NkTAtaIIr-JHw$"><span style="font-weight: 400;">global study</span></a><span style="font-weight: 400;"> on life expectancy showed we are back to pre-pandemic levels with one notable exception: Teens and young adults in Western countries are dying at higher rates, driven largely by suicides and substance use.</span></p>
<p><span style="font-weight: 400;">Traffic fatalities continue to be a major cause of death in young adults, which is one reason The Daily Wire’s Matt Walsh has been vocal about </span><a href="https://www.tiktok.com/@mattwalsh_/video/7559991047514836237"><span style="font-weight: 400;">his opposition</span></a><span style="font-weight: 400;"> to the legalization of marijuana. In fact, a recent study of dead drivers in a major Ohio county morgue found that 42% of them tested </span><a href="https://www.foxnews.com/health/fatal-crash-report-finds-nearly-half-deadly-wrecks-tied-illegal-drug"><span style="font-weight: 400;">positive for THC</span></a><span style="font-weight: 400;">. </span></p>
<p><span style="font-weight: 400;">Pot apologists quickly jumped to their defense, noting that THC can be detected for up to a month after use. But the national past 30-day marijuana use rate </span><a href="https://www.pewresearch.org/short-reads/2025/07/08/facts-about-marijuana/"><span style="font-weight: 400;">is only 16%</span></a><span style="font-weight: 400;">, yet these drivers had average THC levels 5 to 10 times the state legal limits.</span></p>
<p><span style="font-weight: 400;">Some will argue, “Well, it&#8217;s no worse than alcohol.”</span></p>
<p><span style="font-weight: 400;">Marijuana use, however, is associated with </span><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC6296897/#:~:text=Analyses%20revealed:%201)%20daily%20marijuana,marijuana%20use%20and%20negative%20consequences."><span style="font-weight: 400;">more alcohol</span></a><span style="font-weight: 400;"> consumption, and marijuana users are </span><a href="https://www.publichealth.columbia.edu/news/marijuana-smokers-five-times-more-likely-develop-alcohol-problem"><span style="font-weight: 400;">five times</span></a><span style="font-weight: 400;"> more likely to become alcoholics. </span><span style="font-weight: 400;">It has also been reported that up to 40% of marijuana users </span><a href="https://www.pbs.org/newshour/health/daily-marijuana-use-is-now-more-common-than-daily-alcohol-use-in-the-u-s-new-study-finds"><span style="font-weight: 400;">use daily</span></a><span style="font-weight: 400;">, and up to </span><a href="https://urldefense.com/v3/__https://www.yalemedicine.org/conditions/marijuana-use-disorder__;!!JA_k2roV-A!F0P_XFB6ND8ziqH2ovImdot2Tze_kgHA6TLYEc8Ifkn-grY-c9CqSJv-NPamf6v0PFrGk-6w--NkTAta8e51DO8$"><span style="font-weight: 400;">30% meet criteria for addiction</span></a><span style="font-weight: 400;"> — both far higher percentages than for drinkers. Using alcohol to excuse marijuana use or legalization is simply an exercise in lazy whataboutism.</span></p>
<p><span style="font-weight: 400;">Speaking of which, THC strongly induces suicidality even in patients who were not depressed to begin with, and state legalization has led to </span><a href="https://urldefense.com/v3/__https://psychiatryonline.org/doi/10.1176/appi.pn.2025.01.1.15__;!!JA_k2roV-A!F0P_XFB6ND8ziqH2ovImdot2Tze_kgHA6TLYEc8Ifkn-grY-c9CqSJv-NPamf6v0PFrGk-6w--NkTAta6a4o0FY$"><span style="font-weight: 400;">sharp increases</span></a><span style="font-weight: 400;"> in youth suicides. Up to </span><a href="https://urldefense.com/v3/__https://www.scientificamerican.com/article/heavy-cannabis-use-linked-to-schizophrenia-especially-among-young-men/__;!!JA_k2roV-A!F0P_XFB6ND8ziqH2ovImdot2Tze_kgHA6TLYEc8Ifkn-grY-c9CqSJv-NPamf6v0PFrGk-6w--NkTAtaHeiA8hc$"><span style="font-weight: 400;">30% of schizophrenia</span></a><span style="font-weight: 400;"> cases in young men are attributable to THC use now.</span></p>
<p><span style="font-weight: 400;">Marijuana smoke is also causing the same </span><a href="https://www.cnn.com/2024/08/08/health/marijuana-head-and-neck-cancer-wellness/"><span style="font-weight: 400;">type of cancers</span></a><span style="font-weight: 400;"> as tobacco smoke, while also </span><a href="https://www.tctmd.com/news/cannabis-use-again-tied-increased-cvd-risk-young-people"><span style="font-weight: 400;">dramatically increasing</span></a><span style="font-weight: 400;"> the risk of heart attacks and strokes in younger users. Further, as the American College of Cardiology </span><a href="https://www.acc.org/Latest-in-Cardiology/Journal-Scans/2025/06/04/14/21/Chronic-Marijuana-Smoking"><span style="font-weight: 400;">reports</span></a><span style="font-weight: 400;">, THC has been shown to cause damage to major blood vessels regardless of the mechanism of ingestion.</span></p>
<p><span style="font-weight: 400;">Add to this the well-known adverse effects on </span><a href="https://www.imperial.ac.uk/news/124806/long-term-cannabis-blunt-brains-motivation-system/"><span style="font-weight: 400;">motivation</span></a><span style="font-weight: 400;"> and </span><a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC4586361/"><span style="font-weight: 400;">educational</span></a><span style="font-weight: 400;"> achievement, and the costs of the cannabis culture to government budgets are simply staggering. One study on the costs of legalization in Colorado, for example, conservatively </span><a href="https://centennial.ccu.edu/briefs/marijuana-costs/"><span style="font-weight: 400;">estimated</span></a><span style="font-weight: 400;">, “For every dollar gained in tax revenue, Coloradans spent approximately $4.50 to mitigate the effects of legalization.”</span> <span style="font-weight: 400;">And that’s even at a 15% sales tax rate.</span></p>
<p><span style="font-weight: 400;">While there is simply no conservative case for the legalization of marijuana, the libertarian case suffers from serious flaws. First of all, the utopian assumption that legalization would lead to a “safe and regulated” product that would eliminate the black market has now gone 0-for-24 in our marijuana legal states. Many legal THC products are </span><a href="https://urldefense.com/v3/__https://viiahemp.com/collections/high-thc__;!!JA_k2roV-A!F0P_XFB6ND8ziqH2ovImdot2Tze_kgHA6TLYEc8Ifkn-grY-c9CqSJv-NPamf6v0PFrGk-6w--NkTAtaX4gqjCQ$"><span style="font-weight: 400;">more potent</span></a><span style="font-weight: 400;"> than ever before, even more than the now highly potent plant itself. The industry has defied </span><a href="https://www.youtube.com/watch?v=6VkrWO8H08Q"><span style="font-weight: 400;">regulation</span></a>,<span style="font-weight: 400;"> and the black markets are </span><a href="https://alcoholstudies.rutgers.edu/cannabis-black-market-thrives-despite-legalization/"><span style="font-weight: 400;">thriving</span></a><span style="font-weight: 400;">. Legalizing marijuana to eliminate the black market is like giving your dog ticks to rid it of fleas. You just double the infestation.</span></p>
<p><span style="font-weight: 400;">More importantly, substances like THC are the exception that proves the libertarian rule. Libertarianism works when people are free to act in their own best interest and, by extension, their family, community, and country. Chemicals like THC are designed to promote the opposite type of citizen. Libertarians should be the most opposed to the drug culture because it undermines the very foundation of their ideology.</span></p>
<p><span style="font-weight: 400;">The </span><a href="https://learnaboutsam.org/2025/06/leading-experts-warn-marijuana-rescheduling-driven-by-politics-in-stunning-jama-psychiatry-report/"><span style="font-weight: 400;">politically</span></a><span style="font-weight: 400;"> driven potential rescheduling of marijuana will only fuel this destructive industry with tax breaks and marketing privileges. Republicans should note that young male voters </span><a href="https://apnews.com/article/trump-young-men-voters-election-latinos-democrats-ff30e38698a41132cf90345fffabe579"><span style="font-weight: 400;">moved to the Right</span></a><span style="font-weight: 400;"> last November while radical Democrats were still enticing them with more weed.</span></p>
<p><span style="font-weight: 400;">Much attention has been paid to the influence of transgender ideology on the radicalization of Charlie Kirk’s assassin. But as we saw with the transgender school shooter in Minneapolis, THC may have also played a role. As discussed in a </span><a href="https://www.youtube.com/live/Z1b3TYJli5A?si=vXQjsRYLTa6VQdWz&amp;t=1252"><span style="font-weight: 400;">recent episode</span></a><span style="font-weight: 400;"> of the Liz Wheeler show, a close friend of the suspected Utah assassin reported rampant drug use in his apartment and that “We’d have a mostly weekly magic night at the apartment where everyone would come drink, get high and play magic.”</span></p>
<p><span style="font-weight: 400;">Charlie Kirk gave his generation more credit than some in the GOP. Despite the criticism, he stood up to the lies of the THC industry. Republicans will never outbid Democrats in the race to the drug culture bottom. Nor should they, as </span><a href="https://news.gallup.com/poll/648821/americans-views-marijuana-effects-worsen.aspx"><span style="font-weight: 400;">polls show</span></a><span style="font-weight: 400;"> we may have already reached the bottom, with public sentiment now turning against marijuana.</span></p>
<p><span style="font-weight: 400;">Charlie knew that minds can be changed, but facts cannot. Truth and the future of this great country are worth standing for, regardless of the cost. </span></p>
<p><span style="font-weight: 400;">Principled conservatives should do more than eulogize Charlie. They should emulate him.</span></p>
<p>* * *</p>
<p><em><span style="font-weight: 400;">Matt Poling is a physician, Medical Director of Citizens for a Safe and Healthy Texas, and Faculty Advisor for Texas A&amp;M Young Americans for Freedom. </span><a href="mailto:mpoling@sw.org"><span style="font-weight: 400;">mpoling@sw.org</span></a></em></p>
<p><em><span style="font-weight: 400;">The views expressed in this piece are those of the author and do not necessarily represent those of The Daily Wire. </span></em></p>
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Close-up of young adult man rolling a marijuana joint on blur background.

The High Cost Of Getting High: How Legal Weed Is Destroying A Generation

Cannabis: A Cultural Suicide Weapon

Alcohol

China

Drugs

Marijuana

Mental Health

Opinion

<p id="anchor-28fc9b" class="body-graf">Former President Joe Biden is receiving radiation treatment for about five weeks for his advanced prostate cancer, according to a spokesperson.</p>
<p>&#8220;As part of a treatment plan for prostate cancer, President Biden is currently undergoing radiation therapy and hormone treatment,&#8221; the spokesperson said.</p>
<p>Biden has been taking a pill form of hormone medication, <a href="https://www.nbcnews.com/politics/joe-biden/former-president-joe-biden-radiation-therapy-prostate-cancer-rcna237019?cid=sm_npd_nn_tw_ma&amp;taid=68ea5740399eb60001a9aacb&amp;utm_campaign=trueanthem&amp;utm_medium=social&amp;utm_source=twitter">according</a> to NBC News.</p>
<p>The 82-year-old&#8217;s team <a href="https://nypost.com/2025/10/11/us-news/joe-biden-undergoing-radiation-in-new-phase-of-prostate-cancer-treatment-spokesperson-says/?utm_source=twitter&amp;utm_campaign=nypost&amp;utm_medium=social">says</a> Biden is &#8220;doing well.&#8221;</p>
<p>Biden first disclosed his aggressive cancer diagnosis back in May, mere months after he left office. At the time, it was reported that Biden had metastatic prostate cancer that had moved from the prostate all the way to his bones.</p>
<p>&#8220;Cancer touches us all,&#8221; Biden said on X, back in May. &#8220;Like so many of you, Jill and I have learned that we are strongest in the broken places. Thank you for lifting us up with love and support.&#8221;</p>
<blockquote class="twitter-tweet">
<p dir="ltr" lang="en">Cancer touches us all. Like so many of you, Jill and I have learned that we are strongest in the broken places. Thank you for lifting us up with love and support. <a href="https://t.co/oSS1vGIiwU">pic.twitter.com/oSS1vGIiwU</a></p>
<p>— Joe Biden (@JoeBiden) <a href="https://twitter.com/JoeBiden/status/1924427587582828753?ref_src=twsrc%5Etfw">May 19, 2025</a></p></blockquote>
<p>The diagnosis brought well-wishes and prayers from both sides of the political aisle, but it also raised questions &#8212; specifically, when did Biden insiders know about the cancer and how long did they wait to tell the public?</p>
<p>As noted by Daily Wire Editor Emeritus <a href="https://www.dailywire.com/news/biden-was-senile-had-cancer-and-they-knew">Ben Shapiro</a>, prostate cancer is not a fast-moving cancer, and usually takes years to develop to the point of metastasis.</p>
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<p>There have also been questions surrounding Biden&#8217;s mental fitness and his use of the &#8220;autopen&#8221; while he was serving as president.</p>
<p>In June, President Donald Trump <a href="https://www.dailywire.com/news/trump-orders-investigation-into-biden-autopen-scandal">signed a memo</a> ordering an investigation into the matter, specifically calling for Counsel to the President to look into whether aides improperly used an autopen for executive actions in an effort to conceal Biden’s health issues while in office.</p>
<p>The memo directs officials to determine if “certain individuals conspired to deceive the public about Biden’s mental state and unconstitutionally exercise the authorities and responsibilities of the President.”</p>
<p>Additionally, there&#8217;s a<span class="T286Pc" data-sfc-cp="" data-processed="true"> House Oversight Committee investigation into the matter.</span></p>
<p><strong>Related: <a href="https://www.dailywire.com/news/biden-was-senile-had-cancer-and-they-knew">Biden Was Senile, Had Cancer, And They Knew</a></strong></p>


President Biden Hosts Presidential Citizens Medal Ceremony

Biden Team Provides Update On Cancer Battle, Radiation Therapy

Biden Provides Update On Cancer Battle 

Biden Administration

Donald Trump

Joe Biden

Politics

<p>A Los Angeles jury ordered Johnson &amp; Johnson to pay $966 million to the family of a woman who died from mesothelioma, finding the company liable in the latest trial alleging its talc products cause cancer.</p>
<p>The family of Mae Moore, a California resident who died at age 88 in 2021, sued the company the same year, claiming J&amp;J&#8217;s talc baby powder products contained asbestos fibers that caused her rare cancer. The jury late on Monday ordered J&amp;J to pay $16 million in compensatory damages and $950 million in punitive damages, according to court filings.</p>
<p>The verdict could be reduced on appeal as the U.S. Supreme Court has found that punitive damages should generally be no more than nine times compensatory damages.</p>
<p>Erik Haas, Johnson &amp; Johnson&#8217;s worldwide vice president of litigation, said in a statement that the company plans to immediately appeal, calling the verdict &#8220;egregious and unconstitutional.&#8221;</p>
<p>&#8220;The plaintiff lawyers in this Moore case based their arguments on ‘junk science’ that never should have been presented to the jury,&#8221; Haas said.</p>
<p>The company has said its products are safe, do not contain asbestos, and do not cause cancer. J&amp;J stopped selling talc-based baby powder in the U.S. in 2020, switching to a cornstarch product. Mesothelioma has been linked to asbestos exposure.</p>
<p>Trey Branham, one of the attorneys representing Moore&#8217;s family, said after the verdict that his team is “hopeful that Johnson &amp; Johnson will finally accept responsibility for these senseless deaths.”</p>
<p>J&amp;J is facing lawsuits from more than 67,000 plaintiffs who say they were diagnosed with cancer after using baby powder and other talc products, according to court filings. The number of lawsuits alleging talc caused mesothelioma is a small subset of these cases, with the vast majority involving ovarian cancer claims.</p>
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<p>J&amp;J has sought to resolve the litigation through bankruptcy, a proposal that has been rejected three times by federal courts.</p>
<p>Lawsuits alleging talc caused mesothelioma were not part of the last bankruptcy proposal. The company has previously settled some of those claims but has not struck a nationwide settlement, so many lawsuits over mesothelioma have proceeded to trial in state courts in recent months.</p>
<p>In the past year, J&amp;J has been hit with several substantial verdicts in mesothelioma cases, but Monday&#8217;s is among the largest. The company has won some of the mesothelioma trials, including last week in South Carolina, where a jury found J&amp;J not liable.</p>
<p>The company has been successful in reducing some of the awards on appeal, including in one Oregon case where a state judge granted J&amp;J&#8217;s motion to throw out a $260 million verdict and hold a new trial.</p>
<p>(Reporting by Diana Novak Jones; Editing by Alexia Garamfalvi, Rod Nickel and Bill Berkrot)</p>


Johnson & Johnson

Johnson & Johnson Ordered To Pay Staggering Sum In Talc Cancer Case

Courts

Johnson &amp; Johnson

<p><span style="font-weight: 400;">“Dawson’s Creek” actor James Van Der Beek sent a video message to fans during the show’s reunion to make up for not being able to attend.</span></p>
<p><span style="font-weight: 400;">The 48-year-old celeb was forced to drop out of the event at the last minute due to a stomach illness. Van Der Beek has been battling stage 3 colorectal cancer since last year, as he previously announced.</span></p>
<p><span style="font-weight: 400;">“I have been looking forward to this night for months and months ever since my angel Michelle Williams said she was putting it together,” the “Dawson’s Creek” alum said in the recorded message, per </span><a href="https://people.com/james-van-der-beek-makes-surprise-appearance-dawsons-creek-reunion-after-canceling-due-illness-11815128"><span style="font-weight: 400;">People</span></a><span style="font-weight: 400;">. “I can’t believe I’m not there. I can’t believe I don’t get to see my cast mates, my beautiful cast in person.”</span></p>
<p><span style="font-weight: 400;">“And just I want to stand on that stage and thank every single person in the theater for being here tonight,” Van Der Beek continued. “From the cast to the crew to everybody who’s doing anything and has been so generous, and especially every single last one of you – you are the best fans in the world.”</span></p>
<p><span style="font-weight: 400;">&#8220;Thank you for coming. It&#8217;s just absolutely humbling just how much you did for this night, and I just want to say thank you. Thank you to every single person here,&#8221; he said. &#8220;And, obviously, on &#8216;Dawson&#8217;s Creek,&#8217; I had no understudy, but this is Broadway, and I needed one. So we figured we&#8217;d try to find somebody who had never understudied in this theater before.&#8221;</span></p>
<p><span style="font-weight: 400;">The actor had “Hamilton” creator Lin Manuel Miranda take his place at the event, which included a live table read of the pilot episode. The original cast was all in attendance, including Michelle Williams, Katie Holmes, Joshua Jackson, and several others.</span></p>
<p><span style="font-weight: 400;">Van Der Beek’s wife and children were also in the audience at Richard Rodgers Theatre in New York City.</span></p>
<p><span style="font-weight: 400;">The star of the teen drama previously warned fans he wouldn’t be able to make the event with a social media post.</span></p>
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<p><span style="font-weight: 400;">“This is the evening I’d been looking forward to MOST since my angel Michelle Williams said she was putting it together, way back in January,” Van Der Beek shared to Instagram on Monday.</span></p>
<p><span style="font-weight: 400;">“So you can imagine how gutted I was when two stomach viruses conspired to knock me out of commission and keep me grounded at the worst possible moment. Despite every effort… I won’t get to be there. I won’t get to stand on that stage and thank every soul in the theater for showing up for me, and against cancer, when I needed it most.”</span></p>


James Van Der Beek Sends Video Message To ‘Dawson’s Creek’ Reunion After Illness Knocks Him Out

New York City

<p style="font-weight: 400;">A new experimental vaccine has been developed that appears to be successful in preventing recurrences of the deadly colorectal and pancreatic cancers.</p>
<p style="font-weight: 400;">A <a href="https://www.nature.com/articles/s41591-025-03876-4">study</a> led by the Jonsson Comprehensive Cancer Center at the University of California, Los Angeles, tested the ELI-002 2P vaccine on 25 patients previously treated for pancreatic and colorectal cancers.</p>
<p style="font-weight: 400;">The vaccine could “help prevent or delay cancer recurrence in high-risk patients whose tumors are driven by KRAS mutations, which are responsible for half of colorectal cancers and more than 90 percent of pancreatic cancers, researchers noted,” The Hill <a href="https://thehill.com/policy/5458487-new-vaccine-cancer-recurrence-research/">reported.</a></p>
<p style="font-weight: 400;">The patients were tested a year after the vaccine had been administered, and the average relapse-free survival times were significantly greater than historical norms.</p>
<p style="font-weight: 400;">Oncologist Dr. Thomas Marron told <a href="https://www.wane.com/news/promising-vaccine-may-prevent-certain-cancers-from-returning/amp/">NewsNation</a> the results are “extremely promising. Pancreatic cancer and colon cancer are really terrible cancers, and oftentimes even if patients can have curative-intense surgery, unfortunately this cancer tends to come back as microscopic bits of the cancer have already spread. This vaccine is really about teaching patients’ immune system how to recognize and attack those tiny amounts of cancers so that they keep them from coming back, increasing the likelihood that we can cure patients with surgery and chemotherapy or radiation.”</p>
<p style="font-weight: 400;">“Vaccines are all about teaching your immune system to recognize and attack something foreign,” he continued. “Oftentimes we catch colon cancer early because of colonoscopies and sometimes we’ll catch pancreatic cancer early enough so we can do a surgery and cut it out but small amounts remain. So the vaccine is really about teaching your immune system what in the cancer is foreign, because cancer is foreign to our body, and teaching your immune system how to hunt down and  eliminate those tiny bits that remain, and that really increases the likelihood that patients go in remission, stay in remission.”</p>
<p style="font-weight: 400;">The vaccine induced “persistent T cell responses targeting oncogenic driver KRAS mutations, alongside personalized, tumor antigen-specific T cells,” the study found, adding, “Tumor-promoting driver mutations in KRAS occur in approximately 20–25% of human tumors, including colorectal cancer (CRC) (50%) and pancreatic ductal adenocarcinoma (PDAC) (93%). Despite curative intent, relapses are common following standard locoregional therapy, particularly for resectable PDAC.”</p>
<p style="font-weight: 400;">“The long-term follow-up of the AMPLIFY-201 phase 1 study provides evidence that ELI-002 2P induces potent, polyfunctional CD4<sup>+</sup> and CD8<sup>+</sup> T cell immunity to mKRAS alongside frequent antigen spreading that may delay tumor recurrence,” the study stated.</p>


Syringe

‘Extremely Promising’: New Vaccine Could Prevent Recurrence Of Deadly Colon, Pancreatic Cancer

vaccine

<p style="font-weight: 400;">Scientists at the University of Florida in Gainesville are developing a universal cancer vaccine designed to target cancer cells already forming in the body. The vaccine could be especially effective against some of the deadliest cancers, including pancreatic and ovarian cancer.</p>
<p style="font-weight: 400;">The problem in the past has been that because cancers tend to be specific to each person, a cancer vaccine would have to be tailored for that specific individual rather than a one-size-fits-all vaccine, and in the time spent to create a personal vaccine, the cancer could mutate.</p>
<p style="font-weight: 400;">“It can be months from the time you get a patient&#8217;s specimen to when they actually have a personalized therapy,” study senior author and pediatric oncologist Dr. Elias Sayour said, as Live Science <a href="https://www.livescience.com/health/cancer/universal-cancer-vaccine-heading-to-human-trials-could-be-useful-for-all-forms-of-cancer">reports</a>. “The idea that something could be available immediately, albeit in a nonspecific way … could be revolutionary for how we bridge therapy and how we manage patients.”</p>
<p style="font-weight: 400;">The experimental vaccine was discussed in the journal <a style="font-style: inherit; font-weight: inherit;" href="https://go.redirectingat.com/?id=92X1590019&amp;xcust=livescience_us_1632594187414033690&amp;xs=1&amp;url=https%3A%2F%2Fwww.nature.com%2Farticles%2Fs41551-025-01380-1&amp;sref=https%3A%2F%2Fwww.livescience.com%2Fhealth%2Fcancer%2Funiversal-cancer-vaccine-heading-to-human-trials-could-be-useful-for-all-forms-of-cancer" data-analytics-id="inline-link" data-url="https://www.nature.com/articles/s41551-025-01380-1" data-hl-processed="skimlinks" data-placeholder-url="https://go.redirectingat.com/?id=92X1590019&amp;xcust=hawk-custom-tracking&amp;xs=1&amp;url=https%3A%2F%2Fwww.nature.com%2Farticles%2Fs41551-025-01380-1&amp;sref=https%3A%2F%2Fwww.livescience.com%2Fhealth%2Fcancer%2Funiversal-cancer-vaccine-heading-to-human-trials-could-be-useful-for-all-forms-of-cancer" data-google-interstitial="false" data-merchant-name="nature.com" data-merchant-network="SkimLinks" data-mrf-recirculation="[Livescience] Article - Inline Link" data-mrf-link="https://go.redirectingat.com/?id=92X1590019&amp;xcust=livescience_us_4664427368791827916&amp;xs=1&amp;url=https%3A%2F%2Fwww.nature.com%2Farticles%2Fs41551-025-01380-1&amp;sref=https%3A%2F%2Fwww.livescience.com%2Fhealth%2Fcancer%2Funiversal-cancer-vaccine-heading-to-human-trials-could-be-useful-for-all-forms-of-cancer" data-custom-tracking-id="1632594187414033690" data-hawk-tracked="hawklinks" data-label="Nature Biomedical Engineering">Nature Biomedical Engineering</a>; the abstract stated, “Our findings show that the resistance of tumors to immunotherapy is dictated by the absence of a damage response, which can be restored by boosting early type-I interferon responses to enable epitope spreading and self-amplifying responses in treatment-refractory tumors.”</p>
<p style="font-weight: 400;">The experimental vaccine is built on mRNA that triggers cells to produce new proteins, and hopes to strengthen the body to create more type-I interferons, which can locate cancerous tumors.</p>
<p style="font-weight: 400;">Sayour explained that cancer can impede interferon signals and block anti-cancer immune responses, so the experimental vaccine could catalyze an immune “reset.”</p>
<p style="font-weight: 400;">“I personally think this can be used for all forms of cancer,” Sayour stated. “I believe this is a universal paradigm that can be used to treat cancer,” adding that the vaccine could stop a relapse of the cancer after remission.</p>
<p style="font-weight: 400;">“This exciting and novel paper shows promising evidence that giving the immune system a short, targeted boost at just the right time can help previously unresponsive tumors respond to immunotherapy,&#8221; Diana Azzam, from the Center for Advancing Personalized Cancer Treatments at Florida International University, said. “This approach could be especially helpful for ‘cold’ tumors — types of cancer that usually don&#8217;t trigger a strong immune response, like pancreatic, ovarian, and some types of breast cancer.”</p>
<p style="font-weight: 400;">“Sayour and his colleagues have <a style="font-style: inherit; font-weight: inherit;" href="https://clinicaltrials.gov/study/NCT05660408" data-analytics-id="inline-link" data-url="https://clinicaltrials.gov/study/NCT05660408" data-hl-processed="none" data-mrf-recirculation="[Livescience] Article - Inline Link" data-mrf-link="https://clinicaltrials.gov/study/NCT05660408" data-custom-tracking-id="3743527965317849267" data-hawk-tracked="hawklinks" data-google-interstitial="false" data-label="launched a human trial testing a two-hit approach">launched a human trial testing a two-hit approach</a>: an off-the-shelf cancer vaccine followed by a personalized one,” Live Science noted. “This approach saves valuable time needed for personalized vaccinations and may induce rapid immunity that can be further seized upon by personalized therapy,&#8221; Sayour asserted.</p>


Gainesville, University of Florida, campus entrance with students

Breakthrough Cancer Vaccine In The Works At University of Florida

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Medical Research

University of Florida

<p>University of Colorado football coach Deion Sanders announced on Monday that he had been diagnosed with bladder cancer — and that he had undergone a successful surgery to remove the tumor.</p>
<p>Sanders gave a <a href="https://www.espn.com/college-football/story/_/id/45843439/colorado-coach-deion-sanders-said-battled-bladder-cancer" target="_blank" rel="noopener">press conference</a> at the Touchdown Club in the Dal Ward Athletic Center on Monday to update the public on his health, and urged everyone to &#8220;get checked out.&#8221; Sanders appeared alongside Dr. Janet Kukreja, director of urological oncology at University of Colorado Cancer Center, to make the announcement and take questions.</p>
<p>Kukreja began by touting the success of the surgery, saying that Sanders had been declared &#8220;cancer free&#8221; after the surgery was completed. &#8220;The results from the surgery are that he is cured from the cancer.&#8221;</p>
<p>After a brief pause, Sanders quipped, &#8220;You can clap, it&#8217;s ok.&#8221;</p>
<p>The audience laughed and applauded.</p>
<p><strong>WATCH:</strong></p>
<blockquote class="twitter-tweet">
<p dir="ltr" lang="en">&#8220;You have no idea how good God has been to me.&#8221;</p>
<p>Deion Sanders got emotional after revealing he is cured from cancer. <a href="https://t.co/3VDTX0HMFH">pic.twitter.com/3VDTX0HMFH</a></p>
<p>— SportsCenter (@SportsCenter) <a href="https://twitter.com/SportsCenter/status/1949882948590752249?ref_src=twsrc%5Etfw">July 28, 2025</a></p></blockquote>
<p><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></p>
<p>&#8220;It was dynamic. It was tough. It wasn&#8217;t a cakewalk. It wasn&#8217;t easy. That was a fight, but we made it,&#8221; Sanders said, adding, &#8220;You have no idea how good God has been to me.&#8221;</p>
<p>Questions have swirled about Sanders and his health since his son, Deion Sanders Jr., posted a video over the summer in which he could be heard talking about a &#8220;health issue&#8221; he was dealing with: &#8220;I ain&#8217;t all the way recovered.&#8221;</p>
<p>He opted not to address any health-related questions at Big 12 Media Days, further fueling speculation about his condition.</p>
<p>Sanders said on Monday that throughout the ordeal, he has also lost 25 pounds — but that he was ready to return to coaching for the 2025-2026 season.</p>
<p>He followed with a message to the crowd, calling on them to &#8220;get checked out.&#8221;</p>
<p><strong>WATCH:</strong></p>
<blockquote class="twitter-tweet">
<p dir="ltr" lang="en">“Please get yourself checked out… because it could have been a whole other gathering if I hadn’t.”<a href="https://twitter.com/DeionSanders?ref_src=twsrc%5Etfw">@DeionSanders</a> shares a message to everyone during his health update press conference ⬇️ <a href="https://t.co/QBi2v8Ri2L">pic.twitter.com/QBi2v8Ri2L</a></p>
<p>— FOX College Football (@CFBONFOX) <a href="https://twitter.com/CFBONFOX/status/1949882650745065622?ref_src=twsrc%5Etfw">July 28, 2025</a></p></blockquote>
<p><script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></p>
<p>&#8220;Please get yourself checked out, especially African American men, we don&#8217;t like going to the doctors, we don&#8217;t like nothing to do with the doctor, you know that — so I&#8217;m not just talking to the brothers, I&#8217;m talking to my caucasian brothers, my hispanic brothers, my Asian brothers, everybody and my sisters. And that&#8217;s all ya&#8217;ll. Get checked out, because it could have been a whole &#8216;nother gathering if I hadn’t.&#8221;</p>
<p>Watch the full press conference here:</p>
<p><iframe loading="lazy" title="Deion Sanders addresses health issues, reveals he is now cancer free [FULL PRESS CONFERENCE]" width="500" height="281" src="https://www.youtube.com/embed/lasjH5gWMn4?feature=oembed" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" referrerpolicy="strict-origin-when-cross-origin" allowfullscreen></iframe></p>


DEION SANDERS CANCER

Deion Sanders Reveals Cancer Diagnosis, Recovery: ‘You Have No Idea How Good God Has Been To Me’

Deion Sanders Reveals Cancer Diagnosis, Recovery: 'You Have No Idea How Good God Has Been To Me'

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