<p>Puberty blockers, known as gonadotropin-releasing hormone (GnRH) substances, received a warning from U.S. <a href="https://www.dailywire.com/topic/fda">Food and Drug Administration</a> (FDA) officials earlier this month, saying the drug could cause brain swelling, loss of vision, and serious risks for children injecting the hormone.</p>
<p>Officials said a plausible association between using puberty blockers and pseudotumor cerebri, which displays symptoms similar to a brain tumor, was identified in six young girls between the ages of 5 and 12.</p>
<p>&#8220;Five were undergoing treatment for central precocious puberty and one for transgender care,&#8221; FDA officials <a href="https://publications.aap.org/aapnews/news/20636/Risk-of-pseudotumor-cerebri-added-to-labeling-for?autologincheck=redirected">report</a>. &#8220;The onset of pseudotumor cerebri symptoms ranged from three to 240 days after GnRH agonist initiation.&#8221;</p>
<p>Such symptoms in the patients included visual disturbances, headaches, and vomiting. Other effects GnRH agonists caused were an increase in blood pressure, brain swelling, and abducens neuropathy.</p>
<p>A spokesperson from the FDA told <a href="https://www.formularywatch.com/view/fda-updates-safety-labels-for-group-of-gnrh-agonists">Formulary Watch</a> the cases were considered clinically serious and determined that a warning should be added to all GnRH agonist products approved for pediatric patients.</p>
<p>&#8220;Although the mechanism by which GnRH agonists may lead to development of pseudotumor cerebri has not been elucidated, and patients with CPP may have a higher baseline risk of developing pseudotumor cerebri compared with children without CPP,&#8221; the spokesperson said. &#8220;This potential serious risk associated with GnRH agonists justifies inclusion in product labeling.&#8221;</p>
<p>Puberty blockers and hormones have come under fire again after President Joe Biden&#8217;s U.S. Assistant Secretary of Health Rachel Levine asserted that the U.S. should not limit youth access to so-called &#8220;gender-affirming care.&#8221;</p>
<p>&#8220;Gender affirming care is life-saving, medically necessary, age-appropriate, and a critical tool for health care providers,&#8221; Levine <a href="https://www.youtube.com/watch?v=EY0VNzkLHTI&amp;t=20s">said</a>. &#8220;As a pediatrician, when it comes to making sure kids are healthy and happy, I know how important care that affirms someone&#8217;s true identity can be.&#8221;</p>
<p>However, Florida&#8217;s Department of Health has argued the opposite of Levine&#8217;s claims, saying that due to the lack of conclusive evidence, and the potential for long-term and irreversible effects, doctors should not prescribe children 18 years old and younger puberty blockers or hormone therapy.</p>
<p>&#8220;Based on the currently available evidence &#8216;encouraging mastectomy, ovariectomy, uterine extirpation, penile disablement, tracheal shave, the prescription of hormones which are out of line with the genetic make-up of the child, or puberty blockers, are all clinical practices which run an unacceptably high risk of doing harm,'&#8221; Florida&#8217;s Department of Health wrote in a <a href="https://www.floridahealth.gov/_documents/newsroom/press-releases/2022/04/20220420-gender-dysphoria-guidance.pdf?utm_source=floridahealth.gov&amp;utm_medium=referral&amp;utm_campaign=newsroom&amp;utm_content=article&amp;url_trace_7f2r5y6=https://www.floridahealth.gov/newsroom/2022/04/20220420-gender-dysphoria-press-release.pr.html">memo</a>.</p>
<p>Yet Levine claims every major medical association agrees with the comments about “gender-affirming” care saving lives, according to <a href="https://www.foxnews.com/us/florida-dept-health-slams-rachel-levine-character-assassination-trans-youth-comments">Fox News</a>.</p>
<p>Jeremy Redfern, a Florida Health Department spokesperson, denounced Levine&#8217;s so-called data.</p>
<p>&#8220;It&#8217;s an appeal to authority that is in stark contrast to the best available evidence,&#8221; Redfern said.</p>
<p>He said while the state&#8217;s Health Department is following the evidence, the federal government is following the eminence.</p>

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FDA Officials Warn Of Brain Swelling, Vision Loss In Minors Using Puberty Blockers