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Dr. On Malaria Drug: ‘Absolute Game Changer,’ ‘Beginning Of The End Of The Pandemic’
LONDON, UNITED KINGDOM - MARCH 26: In this photo illustration a pack of Hydroxychloroquine Sulfate medication is held up on March 26, 2020 in London, United Kingdom. The Coronavirus (COVID-19) pandemic has spread to many countries across the world, claiming over 20,000 lives and infecting hundreds of thousands more. U.S. President Donald Trump recently promoted Hydroxychloroquine, a common anti-malaria drug, as a potential treatment for COVID-19 when combined with the antibiotic azithromycin. “HYDROXYCHLOROQUINE & AZITHROMYCIN, taken together, have a real chance to be one of the biggest game changers in the history of medicine,” President Trump tweeted last week.
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An infectious disease doctor told Fox News on Wednesday night that using hydroxychloroquine and azithromycin to treat patients that have the coronavirus was an “absolute game changer” and that it was “the beginning of the end of the pandemic.”

Appearing on Fox News’ “The Ingraham Angle” with host Laura Ingraham, Dr. Stephen Smith explained why he believes that the regimen has been effective for treating his patients.

Smith began by explaining what being “intubated” meant, saying it “actually means putting a tube down your trachea and then placed on the ventilator for support, respiratory support.”

“We’ve had, I mentioned 20 intubations, most all of them occurred in the first two days,” Smith continued. “More importantly, no person who has received five days or more of the hydroxychloroquine-azithromycin combination has been intubated. The chance of that occurring by chance, according to my sons who did some stats for me, are .000 something.”

“It’s a ridiculous low no matter how you look at it,” Smith continued. “We worry about selection bias in the situation, but I cannot think of a reason why, if all else is equal, why people that have received five days or more — even four days or more of this hydroxychloroquine-azithromycin regimen wouldn’t get intubated.”

When asked by Ingraham if it was a game changer, Smith responded, “It’s a game changer. It’s an absolute game changer. I think this data will go to really support the French data. Now you actually have an intra[inaudible] comparison saying that this regimen works and I will get some real statisticians besides my sons to look at that.”

“I think this is the beginning of the end of the pandemic,” Smith said. “I’m very serious.”


The New York Times reported on Wednesday that “the malaria drug hydroxychloroquine helped to speed the recovery of a small number of patients who were mildly ill from the coronavirus, doctors in China reported this week.”

“Cough, fever and pneumonia went away faster, and the disease seemed less likely to turn severe in people who received hydroxychloroquine than in a comparison group not given the drug,” the Times added. “Previous reports from China and France that the drug seemed to help patients, along with enthusiastic comments from President Trump, have created a buzz around hydroxychloroquine and the closely related chloroquine, which are decades-old drugs used to treat malaria and autoimmune diseases like lupus and rheumatoid arthritis.”

The Times noted that experts had said that more testing and research was needed on using the treatment to treat the coronavirus but that initial results were promising.

“It’s going to send a ripple of excitement out through the treating community,” said Dr. William Schaffner, an infectious disease expert at Vanderbilt University. “I think it will reinforce the inclination of many people across the country who are not in a position to enter their patients into clinical trials but have already begun using hydroxychloroquine.”

The Times notes that Dr. Schaffner “cautioned that the results applied only to patients with relatively mild illness, like the ones in the study, and could not be generalized to advanced cases.”

The treatment has been touted by President Trump, and members of the administration’s Coronavirus Task Force have remained positive about its potential use to treat coronavirus patients.

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