<p>A team of researchers at the University of Louisville say they have developed a technology that could prevent the COVID-19 virus from infecting human cells by blocking its ability to replicate itself inside the body.</p>
<p>The researchers&#8217; findings were reported Wednesday by the University of Louisville&#8217;s UofL News&#8217; Baylee Pulliam, who covers research and innovation at the university. The &#8220;<a href="https://www.uoflnews.com/section/science-and-tech/uofl-breakthrough-technology-shows-promise-fighting-novel-coronavirus/">breakthrough technology</a>,&#8221; writes Pulliam, &#8220;is believed to block the novel coronavirus SARS-CoV-2 from infecting human cells.&#8221;</p>
<p>&#8220;The technology is based on a piece of synthetic DNA – an &#8216;aptamer&#8217; –  which targets and binds with a human protein called nucleolin,&#8221; Pulliam explains. &#8220;Early tests show that this aptamer may stop viruses, including novel coronavirus, from &#8216;hijacking&#8217; nucleolin to replicate inside the body.&#8221;</p>
<p>Because of the promising results of their early testing, the university is seeking to &#8220;fast-track development, including application to the Food and Drug Administration for approval to start treating patients seriously affected with COVID-19,&#8221; Pulliam writes.</p>
<p>The University of Louisville&#8217;s Paula Bates, John Trent and Don Miller, have applied the aptamer in multiple ways,  Pulliam explains, including as a potential therapeutic drug for some types of cancer.</p>
<p>In response to the coronavirus pandemic, Bates, a professor of medicine, partnered with Kenneth Palmer, director of the university&#8217;s Center for Predictive Medicine for Biodefense and Emerging Infectious Diseases (CPM), to see how the synthetic DNA would impact SARS-CoV-2, the virus that causes COVID-19.</p>
<p>&#8220;I am fortunate to be at UofL, which is one of the few places in the country where we have the facilities to do experiments using the SARS-CoV-2 virus,&#8221; said Bates. The university, Pulliam reports, houses the Regional Biocontainment Laboratory, which is one of just two national biocontainment labs in the country.</p>
<p>Palmer was able to demonstrate through experiments that the aptamer &#8220;was effective against the virus at doses previous research has shown to be safe in patient,&#8221; writes Pulliam.</p>
<p>Along with helping to test the aptamer as a potential treatment for COVID-19, Palmer also is working on Q-Griffithsin, another potential treatment. (<a href="https://www.uoflnews.com/section/science-and-tech/uofl-breakthrough-technology-shows-promise-fighting-novel-coronavirus/">Read UofL News&#8217; full report here</a>.)</p>
<p>While the University of Louisville&#8217;s researchers have found the aptamer to have potential in combating COVID-19, separate studies have also found positive results from other potential treatments. Last week, Gilead Sciences revealed its early findings on tests of its antiviral medicine Remdesivir involving 125 people. Nearly all of the patients who were treated at a Chicago hospital with the antiviral drug experienced &#8220;rapid recoveries in fever and respiratory symptoms&#8221; and were &#8220;discharged in less than a week,&#8221; as reported by <a href="https://www.statnews.com/2020/04/16/early-peek-at-data-on-gilead-coronavirus-drug-suggests-patients-are-responding-to-treatment/">STAT</a>:</p>
<blockquote><p><a href="https://www.statnews.com/2020/03/16/remdesivir-surges-ahead-against-coronavirus/">Remdesivir</a> was one of the first medicines identified as having the potential to impact SARS-CoV-2, the novel coronavirus that causes Covid-19, in lab tests. The entire world has been waiting for results from Gilead’s clinical trials, and positive results would likely lead to fast approvals by the Food and Drug Administration and other regulatory agencies. If safe and effective, it could become the first approved treatment against the disease.</p>
<p>The University of Chicago Medicine recruited 125 people with Covid-19 into Gilead’s two Phase 3 clinical trials. Of those people, 113 had severe disease. All the patients have been treated with daily infusions of remdesivir.</p></blockquote>
<p>The University of Chicago’s Kathleen Mullane, an infectious disease specialist heading up the study, said that only two of the 125 severely ill patients died, while most of them have already been discharged. While the early results look promising, however, researchers stressed that the study is not extensive enough to draw conclusions.</p>
<p><i><span style="font-weight: 400;">The Daily Wire, headed by bestselling author and popular podcast host Ben Shapiro, is a leading provider of conservative news, cutting through the mainstream media’s rhetoric to provide readers the most important, relevant, and engaging stories of the day. Get inside access to The Daily Wire by becoming a</span></i><a href="https://www.dailywire.com/subscribe"> <i><span style="font-weight: 400;">subscriber</span></i></a><i><span style="font-weight: 400;">.  </span></i></p>

<script async src="https://www.instagram.com/embed.js"></script>
<script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>
<script async src="https://www.tiktok.com/embed.js"></script><div data-widget-host="revcontent" data-pub-id="165152" data-widget-id="290588"></div><script src="https://delivery.revcontent.com/165152/290588/widget.js"></script>

University: Research Team Developed ‘Breakthrough Technology’ That Could Block Coronavirus From Infecting Human Cells

One Of Most Sacred Sites For Jews & Christians To Be Fully Opened To Public: ‘Miracle’ Pool Of Siloam

Tuesday | October 5th, 2021

Monday | October 4th, 2021

Friday | October 1st, 2021

Monday | September 27th, 2021

Saturday | September 25th, 2021

News and Commentary

COVID

A video goes viral showing a baby being refused his mother by two gay "dads". This is just the tip of the iceberg, which is why we will have an important discussion today about surrogacy. 

Hour 1

The Matt Walsh Show

Ep. 1765 - This Video Is One Of The Worst Things I've Seen In A Long Time 

The Strait of Hormuz officially opens for business (kind of), the Pope makes “shocking” comments on immigration, and President Trump promises UFO disclosure at TPUSA. 


The Michael Knowles Show

Ep. 1956 -  Pope Leo's "SHOCKING" Immigration Comments EXPLAINED

A false miscreed has corrupted our leadership class.


The Andrew Klavan Show

Ep. 1275 - Dumb, Dumber and Progressive

President Trump announces a 10-day ceasefire between Lebanon and Israel, a murder-suicide involving former Democratic Lieutenant Governor Justin Fairfax shakes Virginia, and France and Britain hold a conference to secure the Strait of Hormuz – after the Iranian conflict ends. Get the facts first with Morning Wire.

- - -

Ep. 2738

- - -

Wake up with new Morning Wire merch: https://bit.ly/4lIubt3

- - -

Today's Sponsors:

Alliance Defending Freedom - Visit https://JoinADF.com/WIRE or text 'WIRE' to 83848 to learn more.

Pocket Hose - Text MORNING to 64000 to get a FREE pocket pivot and their 10-pattern sprayer with the purchase of ANY size Copper Head hose. Message and data rates may apply.

Morning Wire

U.S. Expands Hormuz Blockade & VA Fairfax Deaths Investigated | 4.17.26

U.S. Expands Hormuz Blockade & VA Fairfax Deaths Investigated | 4.17.26 [Member Exclusive]

A ceasefire goes into effect between Israel and Lebanon, a tragic murder-suicide rocks Virginia, and Dairy Queen deploys AI in the drive-thru. Get the facts first with Evening Wire.
- - -
Ep. 2737
- - -
Wake up with new Morning Wire merch: https://bit.ly/4lIubt3 
- - -
Today’s Sponsor:

Alliance Defending Freedom - Visit https://JoinADF.com/WIRE or text “WIRE” to 83848 to learn more.


Menu

— News and Commentary —

University: Research Team Developed ‘Breakthrough Technology’ That Could Block Coronavirus From Infecting Human Cells