<p>President Donald Trump took one last shot at Senator Bill Cassidy as Louisiana headed to the polls on Saturday, urging voters to throw their support behind the incumbent Republican&#8217;s primary challenger.</p>
<p>&#8220;Senator Bill Cassidy of Louisiana is a disloyal disaster,&#8221; the president wrote on <a href="https://truthsocial.com/@realDonaldTrump/posts/116584450399753941">Truth Social</a>, noting that the two-term senator voted to impeach him after the January 6, 2021, Capitol riots. &#8220;Bill Cassidy is a sleazebag, a terrible guy, who is BAD FOR LOUISIANA. Now he’s going to get CLOBBERED, hopefully, in today’s BIG election, by two great people!!!&#8221;</p>
<p>One of those people, Rep. <a href="https://www.dailywire.com/news/senate-slugfest-all-but-inevitable-as-trump-backed-lawmaker-enters-louisiana-race">Julia Letlow</a> (R-LA), earned Trump&#8217;s endorsement shortly after entering the race in January. Letlow, who took office in April 2021 following the death of her husband, Congressman-elect Luke Letlow, has positioned herself as an America First lawmaker and attacked Cassidy from the right.</p>
<p>&#8220;In a state as conservative as ours, we shouldn’t have to wonder how our senator will vote when the pressure’s on,&#8221; Letlow wrote at the launch of her campaign. &#8220;Louisiana deserves conservative champions, leaders who will not flinch.&#8221; Letlow has since endorsed President Trump&#8217;s call for the Senate to eliminate the filibuster in order to pass the <a href="https://x.com/jbletlow/status/2052485326774419954?s=20">SAVE America Act</a>, election integrity legislation that has stalled in the upper chamber.</p>
<p>Letlow also emerged as a supporter of Casey Means, a leading figure in the Make America Healthy Again movement and Trump&#8217;s nominee for surgeon general. Letlow slammed Cassidy for <a href="https://x.com/jbletlow/status/2036859168401859009">holding up</a> Means&#8217;s nomination, calling on him to &#8220;stop dragging his feet, do his job, and help advance President Trump’s agenda.&#8221; Cassidy, a physician, <a href="https://www.statnews.com/2026/02/25/casey-means-bill-cassidy-face-off-on-vaccines/">opposed</a> Means&#8217;s nomination given what he called her &#8220;promotion of vaccine skepticism.&#8221;</p>
<p>Cassidy questioned Robert F. Kennedy Jr. along those lines during the latter&#8217;s Senate hearing, before ultimately voting to confirm him as Secretary of Health and Human Services. He did not relent on Means, however, and Trump late last month <a href="https://www.dailywire.com/news/third-times-the-charm-trumps-new-nominee-for-surgeon-general">pulled her nomination</a>, steering more MAHA ire toward Cassidy.</p>
<p>Louisiana is not the only state where Trump has gotten involved in Republican primaries. The president threw his support behind Ed Gallerin, a retired Navy SEAL challenging Rep. Thomas Massie (R-KY). Massie&#8217;s criticism of the war in Iran and the Trump administration&#8217;s handling of the Jeffrey Epstein files put him firmly in the president&#8217;s crosshairs.</p>
<p>“The incredible people of Kentucky’s 4th Congressional District, who want desperately to get rid of Thomas Massie, the Worst ‘Republican’ Congressman we have had in many years,&#8221; Trump <a href="https://www.dailywire.com/news/thomas-massie-is-a-political-survivor-but-this-time-might-be-different">wrote</a> on Truth Social this month. Trump&#8217;s involvement raised the stakes considerably in the Kentucky race, which has now become the most expensive House primary in American history. Kentucky voters head to the polls on Tuesday.</p>
<p>Letlow has maintained a consistent lead in the polls. On primary day, the RealClearPolitics polling average had her 13 points ahead of Cassidy. Louisiana State Treasurer John Fleming trails Letlow by 8 points, but leads Cassidy by 3. A candidate <a href="https://www.foxnews.com/politics/trump-blasts-sen-bill-cassidy-disloyal-disaster-pushes-challenger-julia-letlow-louisiana-gop-primary">must secure</a> more than 50% of the vote in order to clinch the party&#8217;s nomination. If no candidate crosses that threshold, the top two candidates will head for a June 27 runoff.</p>
<p>The winner of Saturday&#8217;s primary will enter the general election with a heavy advantage over whichever candidate clinches the Democrat nomination, given Louisiana&#8217;s solid Republican tilt. Polls close at 8:00 p.m. ET.</p>

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Trump Slams ‘Disloyal Disaster’ Bill Cassidy As Louisiana Voters Head To The Polls

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Trump Slams ‘Disloyal Disaster’ Bill Cassidy As Louisiana Voters Head To The Polls