FDA Commissioner Dr. Marty Makary joins PragerU CEO Marissa Streit to lay out his bold plan to make the FDA modern, efficient, and focused on health, not profits. They discuss faster approval pathways for lifesaving treatments, cracking down on illegal Chinese vape products, removing toxic food dyes, and lowering drug prices for American families. Dr. Makary also reveals new autism research breakthroughs, efforts to bring drug manufacturing back to the U.S., and practical advice for parents who want to protect their children’s health today.

Note: This interview was filmed prior to the October 1, 2025 government shutdown.

Dennis Prager joins PragerU CEO Marissa Streit from his hospital room with an update on his recovery and a warning that the country’s moral condition may be even more urgent than his own. Dennis reflects on gratitude, suffering, and why he believes America is losing something essential when “America First” turns into “America Only.” He also breaks down the spiritual and ideological forces reshaping the West and explains why the moral case for Israel comes down to one simple question. 

Real Talk with Marissa

Dennis Prager Reflects One Year After His Injury—and Warns of America’s Moral Crisis

Glenn Beck joins PragerU CEO Marissa Streit for a powerful conversation about courage, faith, and what he believes is a spiritual battle for America’s future. At 62, Glenn shares why he now understands his purpose in standing for truth amid rising historical revisionism and hate. He warns against the modern “death cult” spreading on social media and discusses with Marissa the growing confusion between left and right versus right and wrong. Together, they explore the dangers of rage-fueled online culture, how fatherlessness and victimhood narratives are harming young men, and why courage and personal responsibility are essential for restoring strength and sanity.

Glenn Beck Reveals the Hidden War: Dark Forces, Twisted History and the Last Stand for What’s Right

Australian broadcaster–turned–political podcaster Erin Molan joins PragerU CEO Marissa Streit to discuss China’s growing aggression toward the West, the media’s role in fueling division, rising mass immigration, and whether America can maintain its global influence. Erin explains why she left her “dream job” as a top sports anchor in Australia to speak openly about politics, international security, and the spread of radical ideologies throughout Western society.

Erin Molan Says Mass Immigration and Media Lies Are Erasing the West

Jillian Michaels joins PragerU CEO Marissa Streit for a powerful conversation about her evolution from fitness icon to political commentator, and why she felt morally obligated to speak out. Describing herself as a “purple person,” Jillian explains how the transgender medicalization of minors, America’s obesity epidemic, and the corruption of Big Food and Big Pharma pushed her into the public fight, even at personal cost to her family. She also warns that Charlie Kirk’s death has created a dangerous cultural vacuum and calls out major podcasters who are helping mainstream extremist ideas to disaffected young men.

Jillian Michaels Explains the Rise of Extremism and Conspiracy Thinking Among Young Americans

Brandon Tatum joins PragerU CEO Marissa Streit to explore why moral discipline is a rare value in modern society, the crisis of fatherlessness, and how strong men and families shape a healthy nation. They also discuss media propaganda, anti-Israel lies, and the rise of conspiracy culture on the right. Brandon also shares why obedience to God, not popularity, is the key to winning.

Brandon Tatum on Moral Discipline, Rejecting Extremism and Standing with Truth

PragerU CEO Marissa Streit sits down with legendary financier and philanthropist Michael Milken for a discussion on inclusive capitalism, opportunity through innovation, and the future of the American dream. Milken explains what sparked his mission to “democratize capital” and how new technology can lift America again today. They discuss financial literacy, AI in schools, and why family—not wealth—is still the foundation of happiness and resilience.

Self-Made Billionaire Michael Milken on How to Democratize Wealth and Fulfill the American Dream

PragerU CEO Marissa Streit is joined by UC San Diego cosmologist Dr. Brian Keating for a wide-ranging conversation on discovery and skepticism. They discuss everything from the Big Bang theory, UFOs, and moon-landing denial to the existence of God and why good science means “trust—but verify.”

Physicist Dr. Brian Keating Explains UFOs, the Moon Landing, and the Case for God's Existence

What does the future of Israel look like through the eyes of Gen Z? PragerU CEO Marissa Streit sits down with Michael Tal, an IDF demolition specialist who breached Hamas tunnels, and Shabbos Kestenbaum, the Harvard student who sued his university over institutionalized antisemitism. Michael gives a first-hand account of life inside the Hamas tunnels, while Shabbos reveals how Harvard tolerated—and even encouraged—attacks on its Jewish students. Together, they discuss the social-media silence after the peace deal, whether either side truly “won,” and why young people must reclaim a direct, non-politicized relationship with God.

Gen Z on the Gaza War: An IDF Soldier and a Jewish Harvard Grad Discuss the Battles

Commissioner Marty Makary on What MAHA Really Means at the FDA

Civil-rights attorney turned DOJ Assistant Attorney General Harmeet Dhillon joins PragerU CEO Marissa Streit for a wide-ranging conversation on her journey as an immigrant to America, the public’s growing disillusionment with the DOJ, and the rise of lawfare. Dhillon recounts her battles suing for free speech, explains how the DOJ is working to restore equal protection, and weighs in on the future of discourse after Charlie Kirk’s assassination. They also tackle antisemitism on elite campuses, voter-roll integrity, gerrymandering, and why shutting down DEI is essential to ending lawful double standards—and much more.


Can the DOJ Regain the Trust of the American People? Assistant AG Harmeet Dhillon Responds

In this very special interview, PragerU Co-Founder Dennis Prager speaks with PragerU CEO Marissa Streit on camera for the first time since his spinal cord injury in November 2024. Dennis speaks frankly about his current condition, why he’s still happy, and what he believes about God, justice, and the afterlife. Dennis also discusses Charlie Kirk’s legacy (including Charlie’s book dedication to Dennis and his commitment to Shabbat), free speech vs. “hate speech,” the confusion around antisemitism, transgender violence and America’s moral crisis. Finally, Dennis shares the big ideas in his forthcoming book, If There Is No God… The Battle Over Who Defines Good and Evil.

Dennis Prager’s First Public Appearance Since His Injury

PragerU CEO Marissa Streit sits down with Pastor Jack Hibbs to process the nation’s response to the murder of Charlie Kirk—and what it means for the Church. They talk candidly about grief, rising hostility toward people of faith, and how believers can turn heartbreak into prayer, unity, and courage. Pastor Hibbs also examines replacement theology—its roots and how it’s leveraged by political movements, including political Islam—and warns against those who would exploit this moment. Through it all, he reminds us that truth endures and that God can use even tragedy to awaken hearts and nations.

Pastor Jack Hibbs Warns: Don’t Exploit Christianity for Politics and Attention

Charlie Kirk’s murder has left America reeling and asking, “Why, God?” Author Eric Metaxas joins PragerU CEO Marissa Streit to reflect on the life, faith, and courage of their dear friend, Charlie. Eric explains why Charlie’s legacy calls believers to confront evil with goodness, and how his death is igniting a revival of faith in America and beyond.

Eric Metaxas Answers Hard Questions about the Murder of Charlie Kirk

Has America been a force for good or for evil? Why are some podcasters suggesting that the U.S. should have sided with Hitler’s Germany over Churchill’s UK and Stalin’s USSR during World War II? Was dropping the atomic bomb on Hiroshima and Nagasaki a moral failure—or a necessary act to end the war? And does the Constitution really prohibit displaying the Ten Commandments in schools and government buildings? PragerU CEO Marissa Streit invites historians David and Tim Barton for an in-depth discussion. David Barton, founder of WallBuilders, is the author of over 20 books on American history and has served on numerous history advisory boards. Tim Barton, president of WallBuilders, is a national speaker and co-author of The American Story series, known for making America’s founding ideas accessible to students and families.

Is U.S. History Being Twisted to Make America Look Evil? David & Tim Barton Respond

Author and filmmaker Dinesh D’Souza has never been afraid to take on difficult topics with his books and documentaries. Dinesh joins PragerU CEO Marissa Streit for a conversation on immigration, Trump’s policies, the big lie about fascism, and why Israel remains the spiritual center of the world. He also reveals what’s at stake in the global battle between good and evil.

Dinesh D’Souza: The Most Important Issues Facing America Today

Dr. Leonard Sax, physician and psychologist, sits down with PragerU CEO Marissa Streit to expose how toxic culture, weak parenting, and a corrupt medical system have failed our children. They discuss the rising crisis of overmedicated children, the ADHD and antidepressants drugs epidemic, and why the best parenting combines love with firm boundaries.

Dr. Leonard Sax on Why America’s Kids are Depressed, Anxious, and Overmedicated

Hungary’s Prime Minister Viktor Orbán has led his country for over 19 years in total, across two terms. Often criticized by Western media for closing Hungary’s borders, defending Christian values, and resisting EU demands, Orbán sits down with PragerU CEO Marissa Streit in his office to discuss immigration, national identity, family policy, and the cultural battle over Europe’s future—as well as allegations of corruption and how he responds to his critics.

PM Viktor Orbán on Hungary’s Relationship with the EU

Larry Elder joins PragerU CEO Marissa Streit to unpack the first six months of President Trump’s second term, spotlighting key wins on the economy, border security, and foreign policy. The author, lawyer, and former presidential candidate also weighs in on the media’s sudden obsession with the Epstein files. The conversation also explores the rise of third parties, the weaponization of intelligence agencies under Obama-era officials, and what Gavin Newsom’s recent political maneuvers signal about his national ambitions.

Six Months of Trump: Larry Elder on Key Decisions and Controversies

As the Supreme Court weighs in on laws banning gender surgeries, puberty blockers, and hormone treatments for minors, PragerU CEO Marissa Streit sits down with two outspoken physicians on the front lines of this debate. Dr. Stanley Goldfarb, founder of Do No Harm, and Dr. Sheila Nazarian, a board-certified plastic surgeon, challenge the medical establishment’s push for “gender-affirming care” in children. Together, they reveal how political activism and profit incentives are driving irreversible harm, and what recent Supreme Court rulings mean for vulnerable kids.


Doctors Goldfarb and Nazarian: The Evidence Is Clear—Youth Gender Transitions Are a Medical Mistake

MacKenzie Price, co-founder of Alpha Schools and 2 Hour Learning, joins PragerU CEO Marissa Streit to explain how her AI-powered school model is transforming K–12 education. Alpha students are scoring in the top 1–2% nationwide and learning life skills along the way. MacKenzie reveals why the traditional system is broken, how Alpha uses tech to teach thinking and leadership, and why students thrive when they’re given time to pursue their passions.

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