Imagine we&#8217;re back in the late 1980s or early 1990s. You&#8217;re feeling depressed and no one wants to talk to you, so you pay a psychiatrist to listen to your problems. But even after talking things out with your shrink, you&#8217;re still not feeling great. All hope seems lost. Then the shrink tells you not to despair, because you have the opportunity to participate in a clinical trial for a new class of drug that has the potential to cure all of your symptoms, called Selective Serotonin Reuptake Inhibitors, or SSRIs.
If you enter the trial, you have a chance of getting the new SSRI drug, or you could get a placebo that does nothing. You&#8217;re told it&#8217;s a win-win: If you participate in the clinical trial, Big Pharma will get some more data on whether this new class of drugs actually works. And you have a chance of being cured. If you&#8217;re not cured, then in all likelihood, the worst-case scenario isn&#8217;t a big deal. Either you get a placebo and nothing changes, or you get the real drug, which has relatively modest side effects — like dry mouth, nausea, dizziness, and so on. And in exchange for enduring those side effects, your depression might go away. So what do you have to lose?

Democrats Enter Panic Mode As RFK Sets Out To Make America Healthy Again

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Opinion

Big Pharma

Department of Health and Human Services

Depression

Matt Walsh

Robert F. Kennedy Jr.

Science

A video goes viral showing a baby being refused his mother by two gay "dads". This is just the tip of the iceberg, which is why we will have an important discussion today about surrogacy. 

Hour 1

The Matt Walsh Show

Ep. 1765 - This Video Is One Of The Worst Things I've Seen In A Long Time 

The Strait of Hormuz officially opens for business (kind of), the Pope makes “shocking” comments on immigration, and President Trump promises UFO disclosure at TPUSA. 


The Michael Knowles Show

Ep. 1956 -  Pope Leo's "SHOCKING" Immigration Comments EXPLAINED

A false miscreed has corrupted our leadership class.


The Andrew Klavan Show

Ep. 1275 - Dumb, Dumber and Progressive

President Trump announces a 10-day ceasefire between Lebanon and Israel, a murder-suicide involving former Democratic Lieutenant Governor Justin Fairfax shakes Virginia, and France and Britain hold a conference to secure the Strait of Hormuz – after the Iranian conflict ends. Get the facts first with Morning Wire.

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Ep. 2738

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Morning Wire

U.S. Expands Hormuz Blockade & VA Fairfax Deaths Investigated | 4.17.26

U.S. Expands Hormuz Blockade & VA Fairfax Deaths Investigated | 4.17.26 [Member Exclusive]

A ceasefire goes into effect between Israel and Lebanon, a tragic murder-suicide rocks Virginia, and Dairy Queen deploys AI in the drive-thru. Get the facts first with Evening Wire.
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Ep. 2737
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Evening Wire: Lebanon Ceasefire Begins & Murder-Suicide Rocks VA | 4.16.26

The Pendragon Cycle

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Democrats Enter Panic Mode As RFK Sets Out To Make America Healthy Again