What happens when the medication you thought was supposed to help you escape anxiety & depression instead leaves you feeling disconnected from everything you love?

Today, I’m sitting down with Lauren, who shares her authentic, raw experience with post-SSRI sexual dysfunction (PSSD) and the lasting symptoms she says began after taking Zoloft. At 18, she asked all of the right questions about the risks. Years later, she found herself struggling to feel joy, attraction, or even love for her own family–let alone embrace her sexuality as a young woman.

Together, we talk birth control, the shocking normalization of antidepressants among young women, and why Lauren is fighting for better warnings, informed consent, and research to prevent PSSD from happening to the next generation. But we also talk about finding faith and an extraordinary young man who chose to stand beside her through all of it. Her story broke my heart, and her courage gives me hope. This is a conversation we all need to have in America.

Isabel Brown

The Isabel Brown Show

How SSRIs Are Silently Destroying Gen Z, One Zoloft at a Time ft. Lauren Friedman

Every time I open my phone, there’s another update in the Cornell 7 case. New reporting and text messages are raising serious questions, and we need to slow down before letting TikTok decide what happened that night. I wasn’t in that room. Neither were your favorite influencers.

New bombshell reporting from the New York Times and ABC News has published text messages from Jane Doe to several of the 7 fraternity brothers accused of these crimes–and they may impact the entire future of her case.

AND, there’s a much bigger conversation here that I can’t stop thinking about. We’ve spent years telling young women that hookup culture is empowering, monogamy is outdated, and anything goes as long as you say yes. Just because you agree to something doesn’t mean it’s good for you.

I'm breaking down the new reporting and why I believe our culture desperately needs a reset. Sex has to mean something. Our bodies mean something. And we owe the next generation more than pretending there are no consequences.

The Cornell 7 Case Is More Complicated Than TikTok Says

The "Cornell 7" case has taken over the internet, and unfortunately, we have to talk about it. Although the media isn’t going to do it, there are a few VERY important distinctions we need to make in the pursuit of truth. I’m not sure what exactly happened that night or what has happened over the past two years, but these accusations must be taken seriously—for the sake of both the accuser and the defendants.

I wanted to break down what New York law says and what happens next. I called in my good friend & attorney Jordan Berman, aka @unbiasedjordan, to help me understand what this means for Jane Doe, the seven men, and Cornell University.

This story is being updated literally by the hour – so bear with us if we’ve missed something that’s emerged in the last few hours, like the updated coverage of Jane Doe’s conversation with the police – and you can head to Jordan’s podcast Unbiased Politics tomorrow for a full updated breakdown of what you need to know about what’s happening at Cornell & how the law actually plays out.

What do you think about everything in the news about this this week - and what do you think will happen next? Let us know in the comments 👇

Everything You Need To Know About The Cornell 7 Case ft. Unbiased Jordan

When did being a Christian mean hiding from the world? My friend John Cooper, frontman of Skillet, is back, and we’re getting into everything from Halloween and Harry Potter to why Christians are calling seemingly EVERYTHING demonic. There is real evil out there, but are we actually discerning it—or just living in fear?

John shares his story of growing up in a home where Christian rock was off-limits, responding to criticism of his own faith, and reaching people who might never step inside a church. He also opens up about the painful season that inspired Skillet’s new music and finding hope when God feels far away. This conversation made me laugh, challenged me, and reminded me why we cannot give up on bringing light into the darkness.

Is It *Really* Satanic, or Do You Just Not Like It? ft. John Cooper

A Massachusetts bar made masks optional ONE night a week... and somehow that turned into apologies, accusations of ableism, and a three-and-a-half-hour community meeting with a therapist. Yes, really. In the year of our Lord 2026.

Every detail of the drama at the Last Ditch bar in Greenfield, Massachusetts somehow gets more and more ridiculous. From its payment-optional program to a customer base that apparently cannot be appeased, this story had me asking how we’re all living in the same country. If this bar is competing to be the wokest in America, I think they might be winning.

Is The Massachusetts Lesbian Bar Mask Story America's Future?

Having been in the Press Briefing Room myself, I’ve seen up close and personal the people having an absolute meltdown about the "ban" for CNN, MS NOW, and Politico from the White House... and they don’t deserve your sympathy.

Not only is this not REMOTELY a violation of the First Amendment–and free speech is still hugely important for us to continue fighting for–but the very people demanding your outrage have a documented history of hating free speech.

Today we’re getting into what this "ban" really means in the White House Press Pool and who I’d like to see up front in the Press Briefing Room instead of Kaitlyn Collins. Are you upset about this decision from the White House, or hoping to see more independent media covering the government? Let us know what you think in the comments 👇

I Don’t Care Trump Banned CNN, Politico, & MS NOW

We are at a tipping point between AI and humanity, and it’s not as simple as just pulling the plug.

What is America’s responsibility here? What is humanity’s responsibility? And how do we keep this technology out of the hands of terrorists and foreign adversaries?

Today’s conversation with Tristan Harris, AI expert and co-founder of the Center for Humane Technology, honestly terrified me—but it’s one we need to have before it’s too late.

Watch Tristan’s new documentary now on Netflix here 👉https://www.netflix.com/us/title/82792555?s=i&trkid=13747225&shareType=Title&shareUuid=E892E939-1977-4D46-B464-A205111469AD&trg=cp&unifiedEntityIdEncoded=Video%3A82792555&vlang=en

Will Humanity Survive the AI Revolution—or Is It Already Too Late?

As Mitch McConnell returns to Washington this week and shocks the world with scenes of what can only be described as "elder abuse," I have never been more excited about seeing younger people run for Congress.

Michael Alfonso is running to be the youngest person ever elected to the United States House of Representatives in Wisconsin, and his wife Evita Duffy-Alfonso is often found on the campaign trail right alongside him with their brand-new-baby in tow.

We sat down with Michael & Evita last week at the RNC to talk about the issues young Americans actually care about: affording a home, finding a job that can support a family, pro-family policies, motherhood, and whether Republicans can deliver for the next generation. 

Washington desperately needs young leaders who understand what young families are facing—and Michael and Evita are ready to step into the fight.

Move Over Mitch McConnell - It's Michael Alfonso & Gen Z's Time In Congress

Former CIA officer Sarah Adams joins me for an important conversation about how the threat of terrorism has evolved—and why she believes America may not be prepared for what comes next.

Drawing on her years working in counterterrorism, including her service in Benghazi, Sarah breaks down the connections between groups such as al-Qaeda and ISIS, the possibility of extremist cells operating inside the United States, and the warning signs she believes our government is overlooking.

We also talk about political violence, radicalization through social media, the growing influence of Islamist organizations in the West, and the women living under Taliban rule who are risking everything to tell their stories.

It’s a difficult conversation, but one we can’t afford to avoid.

While we’re on the subject – don’t forget that Daily Wire’s new movie Run, Hide, Fight: Infidels is coming out TOMORROW on DW+!! You’ll be able to stream the movie right here 👉 https://www.dailywire.com

Will There Be Another 9/11 In America? I Asked A CIA Analyst

What does the future of the Republican Party look like? At the RNC, I sat down with three young conservative voices to discuss what Gen Z really wants from its leaders heading into the midterms and 2028.

From immigration and affordability to faith, the pro-life movement, and the legacy of Charlie Kirk, one thing is clear: the next generation is tired of weak messaging and watered-down policies. Young conservatives are ready for leaders who will stand firm, speak the truth, and finally go on offense.

What Does Gen Z Want From The Republican Party?

It has been one year without my friend Charlie Kirk. After considering how best to honor his legacy, there was only one clear answer: talking to college students.

I'm joined by three Turning Point USA chapter leaders to discuss how Charlie changed their lives, inspired a generation to return to faith, and transformed conservative activism on college campuses.

As the darkness grows louder, these students are picking up the torch, defending truth, and continuing Charlie’s mission. We miss him terribly—but we will never stop fighting for the future he believed in. Please pray for these college students as they fight the good fight every day.

How Charlie Kirk Forever Changed Generation Z

One year after Charlie Kirk's assassination, people on the Left are openly celebrating what they’re calling "Kirkaversary." They’re throwing parties, mocking his death, and targeting his memorial—all while treating political violence like a joke.

Let them celebrate evil. We'll honor Charlie’s legacy by standing boldly for truth, refusing to back down, and fighting for everything he believed in.

TikTok’s Viral "Kirkaversary" Should Make You Angry One Year After Charlie Kirk

Happy Friday! It’s back to school & back to sports season, which means we’ve got lots of fun to get into on the show today.

The legendary Clay Travis joins me today for a brutally honest conversation about what happens when politics takes over sports. We’re break down the WNBA’s transgender controversy, his $10 million challenge, the chaos of NIL deals, and Colin Kaepernick’s lasting impact on America.

Clay also explains why refusing to apologize helped shape his career—and why standing firm matters more than gaining approval from people who already hate you. Plus, he shares why sports are essential for raising strong, resilient boys, along with the parenting advice every mom and dad needs to hear.

The WNBA Is About To Get An All-Trans Team, Thanks To Clay Travis

Have women completely lost the plot over the Lindsay Clancy trial?

As the jury struggles to reach a unanimous verdict, Allie Beth Stuckey joins me to explain why she changed her mind about the case. We break down Clancy’s medical history, the role of medication, the evidence of planning, and the postpartum diagnoses that were attached to her after the deaths of her three children.

Mental illness deserves compassion—but empathy cannot replace truth, accountability, or justice. So why does so much of the internet seem more concerned with Lindsay than with Cora, Dawson, and Callan?

Why You Should Change Your Mind About Lindsay Clancy

I’M HAVING A BABY BOY! I could not be more excited to welcome our son into the world in just a few short months.

That being said, as I prepared to share the news, I stumbled across a disturbing trend online: women openly calling baby boys a "disappointment" and even celebrating sex-selective abortion.

I had no idea the internet was breeding such hatred toward baby boys, demonizing masculinity, and creating a culture that refuses to let boys grow into men. The world desperately needs more strong, virtuous, and courageous men.

Raising a son may be a brand-new adventure for me, but I’m honored that God chose our family for it.

I’m Pregnant With A BOY & These Responses Will SHOCK You

As the jury deliberates in the Lindsay Clancy trial, a disturbing question is emerging: Should mothers who kill their children receive lesser punishment simply because they recently gave birth?

I had no idea about the infanticide laws across the Western world. And once you see how other countries handle cases like this you will be SHOCKED. 

Under Britain’s Infanticide Act, a mother who kills her child under the age of one can face a lesser charge if her mental state was affected by childbirth or lactation—and prison sentences in these cases are rare. 

Postpartum psychosis is real—but does it excuse murder? And should America follow the UK’s example?

Moms Shouldn't Be Allowed to Kill Their Kids

Closing arguments are over in the Lindsay Clancy trial, and now the jury must decide whether she should be held criminally responsible for killing her three children.

Now we wait for the jury to decide her fate. I have been shocked by the evidence presented in court, the insanity defense, and the disturbing online movement attempting to excuse Lindsay—or even blame her husband. This is not a viral conspiracy theory or a true-crime spectacle. Three innocent children lost their lives, and they deserve justice.

I don’t stand with Lindsay Clancy—and neither should you.

I Don't Stand With Lindsay Clancy & Neither Should You

How does one clip from a family road trip series break the Internet? By hearing two Catholic parents express concerns over their beautiful daughter attending an Ivy League University, of course!

Today on the Isabel Brown Show, Secretary of Transportation Sean Duffy and his wife, Fox & Friends Weekend host Rachel Campos-Duffy join me for a conversation about faith, family, marriage, and raising nine children in today’s culture. We get into their viral Harvard debate, why parents should care about the values their children encounter in college, and their best advice for building a strong, faithful marriage that lasts... even in the middle of swampy Washington, D.C.

Plus, we get into their viral new series The Great American Road Trip, Sean’s plan to fix America’s outdated transportation system, and why strong families may be the most important part of saving America.

https://greatamericanroadtrip.org

You can watch the latest episode of The Great American Road Trip right here 👉 https://www.youtube.com/watch?v=sNeqNzr9GnI

And follow along with Sean and Rachel on social media here 👉https://www.instagram.com/rcamposduffy/ and https://www.instagram.com/secduffy

Why Secretary Sean Duffy Doesn’t Want His Daughter Going To Harvard

I have been getting a crash course (lol... see what I did there 😏) in all things IndyCar this week and I am PUMPED for the Freedom 250 Grand Prix. 

Today I got an exclusive ride along with a former professional IndyCar driver where he took me all the way around the track... I think in less than 60 seconds. I had an absolute blast and I am so grateful that I get to take all of you along with me. 

So maybe you are an avid NASCAR, F1 or IndyCar fan and this event has been on your calendar for months, or maybe you're like me and this is your first time really dipping your toe in. Either way I know you are going to love it.

Also a huge shout out to the American Legion - if you see me riding around DC in a Humvee, hope you think I’m a great driver.

Driving 200 MPH Through Washington, DC | INSIDE LOOK at IndyCar Freedom 250 Grand Prix

American women… we need to talk. As a mom, the Lindsay Clancy trial has been an incredibly difficult case for me to watch—especially as women are coming out in droves to support a woman who violently killed her own three children.

The most horrifying part of this case is undoubtedly the reaction on social media, which turns out is still a pretty dark place. Today’s new “same Lindsey” trend has me sick and embarrassed as a woman. 

How much further are we going to let people kill children in the name of “mental health?” It is high time we advocate for our most vulnerable- both our born and unborn children. 

The Lindsay Clancy case has ignited a difficult conversation about postpartum mental health, personal responsibility, and how we understand a mother accused of killing her own children.

Yes, hormones exist. 

Yes, postpartum depression is real. 

No, these are not excuses for the harming of another life and you should be ashamed if you believe otherwise.

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